CD47 Antibody

SKU: orb1806252

Description

Anti-CD47 Reference Antibody is expressed from CHO. The heavy chain type is huIgG4SP, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.

Images & Validation

• Tested Applications: ELISA, FA, FACS, In vivo
• Reactivity: Human, Mouse

Key Properties

• Clonality: Monoclonal
• Target: CD47
• Source/Expression System: CHO
• Molecular Weight: 145.74 kDa
• Purity: >95%
• Purification: Protein A
• Endotoxin: <0.001 EU/ug
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 100 mM Proline/Acetic acid 20mM Arginine pH 5.0
• Concentration: Batch dependent
• Disclaimer: For research use only

Anti-CD47 Reference Antibody (magrolimab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

The purity of Anti-CD47 Reference Antibody (magrolimab)is more than 98.18% ;determined by SEC-HPLC.

Magrolimab inhibited the tumor growth of Raji on NOD.SCID mice. The result showed significant anti-tumor effects; with an tumor inhibition rate (TGI) of 90.0% at 5 mpk at D32.

Quick Database Links

Gene Symbol

CD47

UniProt

Q08722