Anti-CD47 Reference Antibody (magrolimab)

• Catalog Number: orb1806252
• Category: Antibodies
• Description: Anti-CD47 Reference Antibody is expressed from CHO. The heavy chain type is huIgG4SP, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.
• Target: CD47
• Clonality: Monoclonal
• Isotype: IgG
• Conjugation: Unconjugated
• Reactivity: Human
• Buffer/Preservatives: 100 mM Proline/Acetic acid 20 mM Arginine pH 5.0
• Purity: > 95%
• MW: 145.5 kDa
• Tested applications: ELISA, FA, FACS, Kinetics
• Endotoxins: < 1 EU/mg
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Note: For research use only

Anti-CD47 Reference Antibody (magrolimab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

The purity of Anti-CD47 Reference Antibody (magrolimab)is more than 98.18% ;determined by SEC-HPLC.

Magrolimab inhibited the tumor growth of Raji on NOD.SCID mice. The result showed significant anti-tumor effects; with an tumor inhibition rate (TGI) of 90.0% at 5 mpk at D32.