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Catalog Number | orb1806318 |
---|---|
Category | Antibodies |
Description | Anti-B7-H1 / PD-L1 / CD274 Reference Antibody is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hulambda. It has a predicted MW of 145.5 kDa. |
Clonality | Monoclonal |
Tested applications | ELISA, FA, FACS, Kinetics |
Reactivity | Human |
Isotype | IgG |
Purity | > 95% |
Conjugation | Unconjugated |
MW | 145 kDa |
Target | B7-H1 / PD-L1 / CD274 |
Endotoxins | < 1 EU/mg |
Storage | -80°C |
Buffer/Preservatives | 100 mM Pro-Ac 20 mM Arg pH 5.0 |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Anti-B7-H1 / PD-L1 / CD274 Reference Antibody (avelumab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.
The purity of Anti-B7-H1 / PD-L1 / CD274 Reference Antibody (avelumab)is more than 98.22% ;determined by SEC-HPLC.
Immobilized human PD L1 FC at 2 μg/mL can bind Anti-B7-H1 / PD-L1 / CD274 Reference Antibody (avelumab);EC50=0.03725μg/mL.
Avelumab inhibited the tumor growth of MC38 on hLAG3 mice. The result showed significant anti-tumor effects; with an tumor inhibition rate (TGI) of 32.6% at 1 mpk at D28.
ELISA, FA, FACS, Kinetics | |
Human | |
Monoclonal | |
Unconjugated |
ELISA, FA, FACS, Kinetics | |
Human | |
Monoclonal | |
Unconjugated |
ELISA, FA, FACS, Kinetics | |
Human | |
Monoclonal | |
Unconjugated |
ELISA, FA, FACS, Kinetics | |
Human | |
Monoclonal | |
Unconjugated |
ELISA, FA, FACS, Kinetics | |
Human | |
Monoclonal | |
Unconjugated |
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