Anti-B7-H1 / PD-L1 / CD274 Reference Antibody

• Catalog Number: orb1806315
• Category: Antibodies
• Description: Anti-B7-H1 / PD-L1 / CD274 Reference Antibody is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.
• Clonality: Monoclonal
• Tested applications: ELISA, FA, FACS, Kinetics
• Reactivity: Human
• Isotype: IgG
• Purity: > 95%
• Conjugation: Unconjugated
• MW: 145 kDa
• Target: B7-H1 / PD-L1 / CD274
• Endotoxins: < 1 EU/mg
• Storage: -80°C
• Buffer/Preservatives: 100 mM Pro-Ac 20 mM Arg pH 5.0
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Anti-B7-H1 / PD-L1 / CD274 Reference Antibody (durvalumab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

The purity of Anti-B7-H1 / PD-L1 / CD274 Reference Antibody (durvalumab)is more than 100% ;determined by SEC-HPLC.

Durvalumab inhibited the tumor growth of A375 on NOD.SCID mice. The result showed significant anti-tumor effects; with an tumor inhibition rate (TGI) of 61.2% at 5 mpk at D22.