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Angoline hydrochloride
Catalog Number: orb1981774
| Catalog Number | orb1981774 |
|---|---|
| Category | Small Molecules |
| Description | Angoline hydrochloride (6-Methoxyldihydrochelerythrine) is an IL-6/STAT3 signaling pathway inhibitor isolated from Zanthoxylum nitidum with anticancer activity and inhibits STAT3 signaling. |
| Purity | 98.60% |
| MW | 415.87 |
| Biological Activity | Angoline hydrochloride, a selective inhibitor of the IL6/STAT3 signaling pathway, demonstrates potent activity with an IC50 value of 11.56 μM. It effectively inhibits STAT3 phosphorylation and the expression of its target genes, subsequently reducing cancer cell proliferation [1]. |
| CAS Number | [1071676-04-4] |
| Formula | C22H22ClNO5 |
| SMILES | Cl.O(C=1C=CC=2C3=CC=C4C=C5OCOC5=CC4=C3N(C)C(OC)C2C1OC)C |
| Storage | -20°C |
| Note | For research use only |
Angoline [orb1218462]
> 98% (HPLC)
21080-31-9
379.41
C22H21NO5
500 mg, 200 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 1 g
