AMPK-α1β1γ1 activator 1

SKU: orb1941645

Description

This acyl glucuronide metabolite, derived from an indole-3-carboxylic acid-based activator, is a potent and selective direct activator of the human AMPK α1β1γ1 isoform (EC50 = 38.1 nM). It is a valuable research tool for studying β1-containing AMPK complexes in the context of diabetic nephropathy and other metabolic diseases, applicable in both in vitro and in vivo experimental models.

Research Area

Epigenetics & Chromatin, Signal Transduction

Key Properties

• CAS Number: 1943510-86-8
• MW: 517.91
• Formula: C₂₅H₂₄ClNO₉
• SMILES: C(O[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O)(=O)C=2C=3C(=CC(Cl)=C(C3)C4=CC=C(C=C4)C5(O)CCC5)NC2
• Target: AMPK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

121396411