Amorolfine hydrochloride

SKU: orb1310856

Description

Amorolfine HCl is a morpholine antifungal agent that inhibits ergosterol synthesis by targeting Δ14 reductase and Δ8→Δ7 isomerase, leading to fungal membrane disruption. It is widely used in research for studying antifungal mechanisms and has demonstrated efficacy in both in vitro assays and in vivo models of dermatophyte and yeast infections.

Research Area

Infectious Disease & Virology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 78613-38-4
• MW: 353.97
• Purity: >99.99% (May vary between batches)
• Formula: C₂₁H₃₆ClNO
• SMILES: Cl.CCC(C)(C)c1ccc(CC(C)CN2C[C@H](C)O[C@H](C)C2)cc1
• Target: Antifungal,Antibiotic
• Solubility: H2O:9 mg/mL (25.43 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.83 mM);Ethanol:66 mg/mL (186.46 mM);DMSO:16.67 mg/mL (47.09 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Ro 14-4767/002, vaginal candidiasis, Antibiotic, Amorolfine, Amorolfine HCl, anti-fungal, Fungal, onychomycosis

Compound Identifiers

PubChem CID

54259