Alpha Synuclein Pre-formed Fibrils

SKU: orb1822362

Description

Mouse Recombinant Alpha Synuclein PFFs (Type 1)

Research Area

Neuroscience

Images & Validation

• Tested Applications: In vitro, In vivo, SDS-PAGE, WB
• Application Notes:
  Certified >95% pure using SDS-PAGE analysis. Low endotoxin <5 EU/mL @ 2mg/mL.

Key Properties

• Source: Recombinant
• Expression System: E. coli
• Biological Origin: Mouse
• Biological Activity: Endogenous alpha-synuclein phosphorylation. 100 µM alpha synuclein protein monomer seeded with 10 uM alpha synuclein protein PFF in 25 µM Thioflavin T (PBS pH 7.4, 100 µl reaction volume) generated an increased fluorescence intensity after incubation at 37°C with shaking at 600 rpm. Fluorescence was measured by excitation at 450 nm and emission at 485 nm on a Molecular Devices Gemini XPS microplate reader.
• Target: Alpha Synuclein PFFs
• Reactivity: Mouse
• Tag: No tag
• Protein Length: Full Length
• Purification: Ion-exchange Purified
• MW: ~14.46 kDa
• Purity: >95%
• Protein Sequence: MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH GVTTVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGNIAA ATGFVKKDQM GKGEEGYPQE GILEDMPVDP GSEAYEMPSE EGYQDYEPEA

Storage & Handling

• Storage: -80°C
• Buffer/Preservatives: PBS pH 7.4
• Concentration: 2 mg/ml or 5 mg/ml
• Expiration Date: 6 months from date of receipt.
• Dry Ice Shipping: Please note: This product requires shipment on dry ice. A dry ice surcharge will apply.
• Disclaimer: For research use only

Alternative Names

Alpha synuclein PFFs, Alpha synuclein PFF, Alpha synuclein aggregates, Alpha synuclein protein aggregates, Alpha synuclein aggregates, Alpha-synuclein protein, Non-A beta component of AD amyloid protein, Non-A4 component of amyloid precursor protein, NACP protein, SNCA protein, NACP protein, PARK1 protein, SYN protein, Parkinson's disease familial 1 Protein

Quick Database Links

Gene Symbol

Alpha Synuclein PFFs

UniProt

O55042