A 83-01

• Catalog Number: orb1304606
• Category: Small Molecules
• Description: A 83-01
• CAS Number: 909910-43-6
• Purity: 98.76%
• MW: 421.52
• SMILES: C(NC1=CC=CC=C1)(=S)N2C=C(C(=N2)C=3N=C(C)C=CC3)C=4C5=C(N=CC4)C=CC=C5
• Formula: C₂₅H₁₉N₅S
• Biological Activity: A 83-01 (ALK5 Inhibitor IV) is an inhibitor of the TGF-β type I receptors ALK5, ALK4, and ALK7 (IC50=12/45/7.5 nM). A 83-01 promotes the reprogramming of mouse fibroblasts into iPSCs. A 83-01 can be used in organoid cultures.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.