YKL-5-124 TFA

SKU: orb1983579

Description

YKL-5-124 TFA is a highly selective, irreversible covalent inhibitor of CDK7, demonstrating potent activity against both isolated CDK7 and the CDK7/Mat1/CycH complex. It induces cell-cycle arrest and suppresses E2F-driven transcription in vitro, making it a valuable chemical probe for studying transcriptional regulation and cell-cycle control in cancer research.

Research Area

Cell Biology

Key Properties

• CAS Number: 2748220-93-9
• MW: 629.63
• Formula: C₃₀H₃₄F₃N₇O₅
• SMILES: C(C(O)=O)(F)(F)F.N(C(=O)C1=CC=C(NC(C=C)=O)C=C1)C=2C3=C(C(C)(C)N(C(N[C@H](CN(C)C)C4=CC=CC=C4)=O)C3)NN2
• Target: CDK,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

146025947