YKL-5-124 TFA (1957203-01-8 free base)

SKU: orb1708201

Description

YKL-5-124 TFA is a potent, selective, and covalent inhibitor of CDK7, demonstrating IC50 values of 53.5 nM against CDK7 and 9.7 nM against the CDK7/Mat1/CycH complex. This compound is a valuable chemical probe for investigating CDK7's roles in transcription and cell cycle progression in both in vitro biochemical and cellular assays.

Research Area

Immunology & Inflammation

Key Properties

• MW: 629.63
• Formula: C₃₀H₃₄F₃N₇O₅
• SMILES: CC1(C)N(C(N[C@@H](C2=CC=CC=C2)CN(C)C)=O)CC3=C1NN=C3NC(C4=CC=C(NC(C=C)=O)C=C4)=O.FC(F)(C(O)=O)F
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

146025947