XPO1/CRM1 Antibody

SKU: orb1537626

Description

XPO1/CRM1 Antibody

Research Area

Cancer Biology

Images & Validation

• Tested Applications: IHC, IHC-P, WB
• Dilution Range: IHC, IHC-P (10 µg/ml), WB (1 - 3 µg/ml)
• Reactivity: Bovine, Canine, Equine, Gallus, Human, Mammal, Monkey, Xenopus
• Application Notes:
  Further information: Immunohistochemistry: This was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration was determined to be 10 ug/ml.

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Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Immunogen: Amino acids 390-408 (ASPLLSGSQHFDVPPRRQL) of human Exportin-1 protein were used as the immunogen. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Elephant, Panda, Bovine, Dog, Bat, Horse, Chicken, Platypus, Xenopus (100%); Mouse, Rat, Hamster, Rabbit, Opossum, Zebrafish (95%); Stickleback, Pufferfish (89%).
• Target: XPO1 / CRM1
• Purification: Protein G purified
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: PBS, 0.05% Sodium Azide, 0.2% Gelatin
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

XPO1, CRM1, yeast, homolog, Exp1, Exportin-1, CRM1

Quick Database Links

Gene Symbol

XPO1 / CRM1