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Catalog Number | orb1303863 |
---|---|
Category | Small Molecules |
Description | XMD16-5 |
CAS Number | 1345098-78-3 |
Purity | 99.60% |
MW | 416.48 |
SMILES | CN1C=2C(NC(=O)C=3C1=CC=CC3)=CN=C(NC4=CC=C(C=C4)N5CCC(O)CC5)N2 |
Formula | C23H24N6O2 |
Biological Activity | XMD16-5 is a TNK2 inhibitor. TNK2 genomic amplification has been associated with late-stage or metastatic lung and prostate Ys. Overexpression of TNK2 promoted metastasis in a mouse model of breast Y. TNK2 signaling is disrupted in breast, prostate and gastrointestinal tumors. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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