XMD-17-51 Trifluoroacetate

SKU: orb1298297

Description

XMD-17-51 Trifluoroacetate is a pyrimido-diazepinone-based small molecule functioning as a protein kinase modulator. It is utilized in biochemical and cellular research to investigate kinase signaling pathways in both in vitro assays and in vivo model systems.

Research Area

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction

Key Properties

• CAS Number: 2436579-93-8
• MW: 518.49
• Purity: 99.65%
• Formula: C₂₃H₂₅F₃N₈O₃
• SMILES: OC(=O)C(F)(F)F.CN1c2ccccc2C(=O)N(C)c2cnc(Nc3cnn(c3)C3CCNCC3)nc12
• Target: Bcr-Abl,Others,PLK,AMPK,ERK,Trk receptor,Kinesin
• Solubility: 10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (6.36 mM);Ethanol:8 mg/mL (15.43 mM);H2O:2 mg/mL (3.86 mM);DMSO:80 mg/mL (154.29 mM)

Bioactivity

• In Vitro:
  XMD-17-51 Trifluoroacetate is a pyrimido-diazepinone compound proficient in modulating an extensive range of protein kinases, such as MPS1 (TTK), ERK5 (BMK1, MAPK7), various polo kinases, Ack1, Ack2, Abl and its mutants, DCAMKL1, ABL1, DCAMKL2, and many others including Bcr-Abl, GAK, cSrc, and Trk family proteins. This versatility renders it applicable in treating a diverse array of diseases, disorders, or conditions .

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

1628614-50-5, 1628614-50-5 free base, NUAK1, XMD 17 51 Trifluoroacetate, XMD1751 Trifluoroacetate, XMD-17-51 Trifluoroacetate, XMD-17-51 Trifluoroacetate (1628614-50-5 free base)

Compound Identifiers

PubChem CID

134821692