XD2-149

SKU: orb2665319

Description

XD2-149 is a PROTAC compound designed to target STAT3. It is composed of the PROTAC target protein ligand Napabucasin, the E3 ligase Thalidomide, and the linker NH2-C5-Azacyclohexane-N-Boc. The conjugate of the E3 ligase and linker is Thalidomide-NH-C5-azacyclohexane-N-Boc, with Thalidomideacid serving as the active comparator for the target protein ligand.

Key Properties

• CAS Number: 2710221-08-0
• MW: 693.75
• Formula: C₃₈H₃₉N₅O₈
• SMILES: O=C(NCCN1CCC(CC1)CCCCCNC2=CC=CC=3C(=O)N(C(=O)C23)C4C(=O)NC(=O)CC4)C=5OC=6C(=O)C=7C=CC=CC7C(=O)C6C5
• Target: STAT,PROTACs

Storage & Handling

• Storage: -20°C
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

STAT,PROTACs