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XD2-149
Catalog Number: orb1910989
| Catalog Number | orb1910989 |
|---|---|
| Category | Small Molecules |
| Description | XD2-149 is a napabucasin PROTAC as an effective degrader of the E3 ligase ZFP91 with IC50 of 1 μM and 0.8 μM in pancreatic cancer cell lines, MIA PaCa-2 and BxPC-3, respectively. XD2-149 also reduces the expression of STAT3, pSTAT3, and NQO1 proteins. |
| MW | 693.757 |
| SMILES | O=C(CC1)NC(C1N(C2=O)C(C3=C2C(NCCCCCC(CC4)CCN4CCNC(C(O5)=CC6=C5C(C7=C(C6=O)C=CC=C7)=O)=O)=CC=C3)=O)=O |
| Formula | C38H39N5O8 |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
