X396

SKU: orb3033026

Description

Ensartinib, also known as X-396, is an orally available small molecule inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) with potential antineoplastic activity. Upon oral administration, X-396 binds to and inhibits ALK kinase, ALK fusion proteins and ALK point mutation variants. Inhibition of ALK leads to the disruption of ALK-mediated signaling and eventually inhibits tumor cell growth in ALK-expressing tumor cells. ALK belongs to the insulin receptor superfamily and plays an important role in nervous system development.

Key Properties

• CAS Number: 1370651-20-9
• MW: 561.435386896133
• Purity: >98%
• Formula: C₂₆H₂₇CL₂FN₆O₃
• SMILES: C1(C(NC2=CC=C(C(N3C[C@H](C)N[C@H](C)C3)=O)C=C2)=O)=NN=C(N)C(O[C@@H](C2=C(Cl)C=CC(F)=C2Cl)C)=C1

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only