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WRX606

SKU: orb2646360

Description

WRX606 is a potent mTORC1 inhibitor, suppressing p-S6K1 (IC50=10 nM) and p-4E-BP1 (IC50=0.27 µM) in MCF-7 cells. It demonstrates cytotoxicity in HepG2 cells (IC50=17 nM) and has shown antitumor activity in mouse models, supporting its use in cancer research.

Research Area

Signal Transduction

Images & Validation

Key Properties

CAS Number899937-47-4
MW548.97
FormulaC28H25ClN4O6
SMILESO=C(NC=1C=CC=C(Cl)C1)CN2C(=O)N(C(=O)C=3C=CC=CC32)CCCC(=O)NCC4=CC=C5OCOC5=C4
TargetmTOR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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  • WRX606 [orb1910987]

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    C28H25CLN4O6

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

WRX606 (orb2646360)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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