WRN inhibitor 7

SKU: orb2565054

Description

WRN inhibitor 7 (Compound h6) is a potent small molecule targeting Werner syndrome helicase, inhibiting its helicase and ATPase activities with IC50 values of 9.8 µM and 15.8 µM, respectively. It is a valuable research tool for studying DNA repair mechanisms and synthetic lethality in microsatellite instable (MSI) cancer models in vitro.

Research Area

Cell Biology, Epigenetics & Chromatin; Pharmacology & Drug Discovery, Molecular Biology

Key Properties

• CAS Number: 444780-45-4
• MW: 485.49
• Formula: C₂₇H₂₃N₃O₆
• SMILES: C(=C1C(=O)N(CC(NC2=CC=C(C)C=C2)=O)C(=O)N1)C3=C(OCC4=CC(C(O)=O)=CC=C4)C=CC=C3
• Target: DNA/RNA Synthesis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

72182265