WRN inhibitor 13

SKU: orb2945699

Description

WRN inhibitor 13 is a potent small molecule targeting the Werner syndrome helicase (WRN), exhibiting inhibitory activity with a pIC50 of 6-7. It is a valuable research tool for studying DNA repair mechanisms and synthetic lethality in microsatellite unstable cancers, applicable in both cellular and biochemical assays.

Research Area

Cell Biology, Epigenetics & Chromatin; Pharmacology & Drug Discovery, Molecular Biology

Key Properties

• CAS Number: 2923009-51-0
• MW: 352.405
• Formula: C₁₆H₂₀N₂O₅S
• SMILES: OC1=C(NC(=O)C(C(N[C@H]2C=CS(=O)(=O)C2)=O)=C1)C3CCCCC3
• Target: DNA/RNA Synthesis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168205685