WRN inhibitor 17

SKU: orb2814420

Description

WRN inhibitor 17 (Compound 250) is an orally bioavailable small molecule that selectively targets the helicase domain of Werner syndrome ATP-dependent helicase (WRN). This inhibitor is a valuable research tool for investigating WRN's role in microsatellite unstable (MSI) cancers, with utility in both in vitro and in vivo preclinical studies.

Research Area

Cell Biology, Epigenetics & Chromatin; Pharmacology & Drug Discovery, Molecular Biology

Key Properties

• CAS Number: 3064599-40-9
• MW: 690.71
• Formula: C₃₃H₃₄F₄N₄O₆S
• SMILES: C(O)(=O)[C@@H]1[C@H](C[C@@H](COC)C[C@H]1C(NC2=C(F)C=C(C(F)(F)F)C=C2)=O)C3=CC=C(N(S(=O)(=O)C=4C=C5C(=CC4)N(C)C(C)=N5)C)C=C3
• Target: DNA/RNA Synthesis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172617599