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Catalog Number | orb1300904 |
---|---|
Category | Small Molecules |
Description | Wortmannin |
CAS Number | 19545-26-7 |
Purity | 99.76% |
MW | 428.43 |
SMILES | C[C@@]12C3=C([C@]4([C@](C)(C[C@H]3OC(C)=O)C(=O)CC4)[H])C(=O)C5=C1C(C(=O)O[C@@H]2COC)=CO5 |
Formula | C23H24O8 |
Biological Activity | Wortmannin (SL-2052) is a PI3K inhibitor (IC50=3 nM) that is covalent and irreversible. Wortmannin is also an inhibitor of PlK1 and PlK3 (IC50=5.8/48 nM) that blocks autophagy. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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