Wnt5a Antibody

• Catalog Number: orb1731189
• Category: Antibodies
• Description: Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression.
• Species/Host: Rabbit
• Clonality: Monoclonal
• Tested applications: ICC, WB
• Reactivity: Human
• Isotype: Rabbit IgG
• Immunogen: A synthetic peptide of human Wnt5a
• Concentration: 1mg/ml
• Dilution range: WB: 1/500-1/1000; ICC: 1/50-1/200
• Conjugation: Unconjugated
• MW: Calculated MW: 42 kDa; Observed MW: 45 kDa
• Entrez: 7474
• UniProt ID: P41221
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% rAlbumin
• Alternative names: WNT5A; Protein Wnt-5a
• Note: For research use only
• Expiration Date: 12 months from date of receipt.