Wnt5a Antibody

• Catalog Number: orb1730359
• Category: Antibodies
• Description: Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: FC, ICC, WB
• Reactivity: Human
• Isotype: Rabbit IgG
• Immunogen: A synthesized peptide derived from human Wnt5a
• Dilution range: WB: 1/500-1/1000; ICC: 1/50-1/200; RCM: 1/50-1/100
• Conjugation: Unconjugated
• MW: Calculated MW: 42 kDa; Observed MW: 42 kDa
• Entrez: 7474
• UniProt ID: P41221
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Alternative names: WNT5A; Protein Wnt-5a
• Note: For research use only
• Expiration Date: 12 months from date of receipt.