VU0071063

SKU: orb1305240

Description

VU0071063 is a small molecule activator of the Kir6.2/SUR1 pancreatic KATP channel complex. It is a valuable research tool for studying insulin secretion mechanisms and diabetes pathophysiology in both cellular and isolated tissue experimental models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 333415-38-6
• MW: 326.39
• Purity: 99.99% (May vary between batches)
• Formula: C₁₈H₂₂N₄O₂
• SMILES: Cn1c2ncn(Cc3ccc(cc3)C(C)(C)C)c2c(=O)n(C)c1=O
• Target: Potassium Channel
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.13 mM);DMSO:50 mg/mL (153.19 mM)

Bioactivity

• Target IC50:
  KIR6.2/SUR1:7.44 μM (EC50)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Specific, Potent, PotassiumChannel, Potassium Channel, VU 0071063, VU0071063, VU-0071063, inhibit, KcsA, Kir6.2/SUR1, Insulin, Inhibitor, Hyperpolarization, B-cell, Alzheimer

Compound Identifiers

PubChem CID

590142