VU 0357017 hydrochloride

SKU: orb1223424

Description

VU0357017, also known as CID 25010775, is a subtype-selective M1 muscarinic acetylcholine allosteric agonist.

Images & Validation

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Key Properties

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CAS Number	1135242-13-5
MW	369.89
Purity	>98% (HPLC)
Formula	C₁₈H₂₈ClN₃O₃
SMILES	CCOC(=O)N1CCC(CC1)NCCNC(=O)c1ccccc1C.Cl
Target	M1 mAChR
Solubility	DMSO : ≥ 33 mg/mL 89.22 mM

Bioactivity

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In Vivo	Animal model: Male Sprague Dawley rats (380-420 g) were pretreated with scopolamine. Dosage: 1, 3, 10 mg/kg. Administration: A single i.p. Result: Produced a significant reversal of the scopolamine-induced deficits at a dose of 10 mg/kg.

Storage & Handling

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Storage	Storage temperature: -20°C. Stability: ≥ 2 years
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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VU0357017, VU-0357017, VU 0357017, CID 25010775

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Quick Database Links

Gene Symbol

M1 mAChR

Protocol Information

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Purity:	99.97% (May vary between batches)
CAS Number:	1135242-13-5
MW:	369.89
Formula:	C₁₈H₂₈ClN₃O₃