Veratridine

SKU: orb1987226

Description

Veratridine is a benzoate-cevane found in Veratrum and Schoenocaulon. It activates sodium channels to stay open longer than normal.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 71-62-5
• MW: 673.79
• Purity: 99.27%
• Formula: C₃₆H₅₁NO₁₁
• SMILES: [H][C@@]12CC[C@@]3([H])[C@]4(O)C[C@H](O)[C@@]5(O)[C@@]([H])(CN6C[C@@H](C)CC[C@@]6([H])[C@@]5(C)O)[C@]4(O)C[C@@]33O[C@]1(O)[C@H](CC[C@@]23C)OC(=O)c1ccc(OC)c(OC)c1
• Target: Sodium Channel
• Solubility: DMSO:10 mM;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.97 mM)

Bioactivity

• Target IC50:
  Nav1.7:18.39 μM

Storage & Handling

• Storage: store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Disclaimer: For research use only

Alternative Names

voltage-gated sodium channels, Veratridine, SodiumChannel, Sodium Channel, DRG neurons, 3-Veratroylveracevine, Inhibitor, Liliaceae, inhibit, Nav1.7, Neuro-2a, Na channels, Na+ channels

Compound Identifiers

PubChem CID

6280