Nav1.7-IN-13

SKU: orb3133894

Description

Nav1.7-IN-13 (compound 3g) is a sodium channel inhibitor that notably suppresses Veratridine-induced neuronal activity. It inhibits the total Na+ current in DRG neurons in a concentration-dependent manner and delays the activation of Navs. Nav1.7-IN-13 significantly alleviates mechanical pain behavior in a rat model of nerve injury (SNI), exhibiting analgesic properties.

Key Properties

• CAS Number: 2776235-57-3
• MW: 472.33
• Formula: C₂₃H₂₂BrNO₅
• SMILES: C(OC)(=O)[C@@]1(CC=2C(O1)=CC=CC2)[C@@]3(O)C=4C(N(CC=C(C)C)C3=O)=CC(Br)=CC4
• Target: Sodium Channel

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Sodium Channel