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Vanilloid receptor antagonist 1

SKU: orb1298246

Description

This small molecule is a potent and selective antagonist of the TRPV1 (vanilloid) receptor, with the chemical structure 4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile. It is a valuable research tool for studying pain, neurogenic inflammation, and thermal sensation in both in vitro cellular assays and in vivo animal models.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number871814-52-7
MW305.33
Purity98.77% (May vary between batches)
FormulaC18H15N3O2
SMILESCC(C)c1nc2cc(O)ccc2c(=O)n1-c1ccc(cc1)C#N
TargetTRP/TRPV Channel
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.55 mM);DMSO:50 mg/mL (163.76 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

inhibit, Inhibitor, 4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile, TRP Channel, TRPVChannel, TRPV1, TRPChannel, TRPV Channel, Transient receptor potential channels, Vanilloid receptor antagonist 1, Vanilloid receptor antagonist1, Vanilloid receptor antagonist-1

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 ml x 10 mM (in DMSO)
$ 70.00
1 mg
$ 100.00
5 mg
$ 190.00
10 mg
$ 270.00
25 mg
$ 420.00
50 mg
$ 580.00
100 mg
$ 810.00
DispatchUsually dispatched within 5-10 working days
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