Val-cit-PAB-OH

SKU: orb1307626

Description

Val-cit-PAB-OH is a cleavable linker used in the development of antibody-drug conjugates (ADCs). This protease-sensitive spacer enables targeted drug release and is widely utilized in both in vitro and in vivo cancer research to enhance therapeutic efficacy and specificity.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 159857-79-1
• MW: 379.45
• Purity: 99.11% (May vary between batches)
• Formula: C₁₈H₂₉N₅O₄
• SMILES: CC(C)[C@H](N)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(CO)cc1
• Target: PROTAC Linker,ADC Linker
• Solubility: DMSO:100 mg/mL (263.54 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.54 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cleavable, Antibody-drug conjugates linkers, ADCLinker, ADC Linkers, ADC Linker, Inhibitor, inhibit, Val cit PAB OH, ValcitPABOH, Val-cit-PAB-OH

Compound Identifiers

PubChem CID

54387473