Mal-PEG4-Val-Cit-PAB-OH

SKU: orb1989109

Description

Mal-PEG4-Val-Cit-PAB-OH is a protease-cleavable linker used in constructing antibody-drug conjugates (ADCs) for targeted cancer therapy. It enables the controlled release of cytotoxic payloads in both in vitro and in vivo research models, facilitating the study of ADC efficacy and stability.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 2055041-39-7
• MW: 706.794
• Formula: C₃₃H₅₀N₆O₁₁
• SMILES: CC(C)[C@H](NC(=O)CCOCCOCCOCCOCCN1C(=O)C=CC1=O)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(CO)cc1 |c:24,@@:1|
• Target: PROTAC Linker,ADC Linker

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

119058241