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Catalog Number | orb2279083 |
---|---|
Category | Small Molecules |
Description | Val-Ala-PABC-Exatecan is a Drug-Linker Conjugate for Antibody-Drug Conjugate (ADC) synthesis, comprising a cleavable Tesirine linker (Val-Ala-PABC) and the topoisomerase I inhibitor Exatecan. It is used in the construction of ADC molecules, including Mal-PEGn-amide-va-Exatecan [1]. |
CAS Number | 2845164-91-0 |
Purity | 98.00% |
MW | 754.8 |
SMILES | N(C(OCC1=CC=C(NC([C@@H](NC([C@H](C(C)C)N)=O)C)=O)C=C1)=O)[C@@H]2C3=C4C(C=5N(C4)C(=O)C6=C(C5)[C@](CC)(O)C(=O)OC6)=NC=7C3=C(CC2)C(C)=C(F)C7 |
Formula | C40H43FN6O8 |
Biological Activity | Val-Ala-PABC-Exatecan is a Drug-Linker Conjugate for Antibody-Drug Conjugate (ADC) synthesis, comprising a cleavable Tesirine linker (Val-Ala-PABC) and the topoisomerase I inhibitor Exatecan . It is utilized in the construction of ADC molecules, including Mal-PEGn-amide-va-Exatecan [1]. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
98.00% | |
2928571-45-1 | |
868.83 | |
C42H44F4N6O10 |