Val-Ala-PABC-Exatecan trifluoroacetate

• Catalog Number: orb2283474
• Category: Small Molecules
• Description: Val-Ala-PABC-Exatecan trifluoroacetate is a drug-linker conjugate for antibody-drug conjugates (ADC), comprising a cleavable Tesirine linker, Val-Ala-PABC, and the topoisomerase I inhibitor Exatecan. This compound facilitates the synthesis of ADC molecules, including Mal-PEGn-amide-va-Exatecan [1].
• CAS Number: 2928571-45-1
• Purity: 98.00%
• MW: 868.83
• SMILES: C(C(O)=O)(F)(F)F.N(C(OCC1=CC=C(NC([C@@H](NC([C@H](C(C)C)N)=O)C)=O)C=C1)=O)[C@@H]2C3=C4C(C=5N(C4)C(=O)C6=C(C5)[C@](CC)(O)C(=O)OC6)=NC=7C3=C(CC2)C(C)=C(F)C7
• Formula: C₄₂H₄₄F₄N₆O₁₀
• Biological Activity: Val-Ala-PABC-Exatecan trifluoroacetate is a drug-linker conjugate for antibody-drug conjugates (ADC), comprising a cleavable Tesirine linker, Val-Ala-PABC, and the topoisomerase I inhibitor Exatecan. This compound facilitates the synthesis of ADC molecules, including Mal-PEGn-amide-va-Exatecan [1].
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.