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V-0219

SKU: orb1301197

Description

V-0219 is a small molecule positive allosteric modulator of the GLP-1 receptor. It is a useful research tool for investigating metabolic disorders, including obesity-associated diabetes, in both in vitro and in vivo experimental models.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number878453-71-5
MW410.43
Purity99.91%
FormulaC20H25F3N4O2
SMILESFC(F)(F)C=1C=CC(=CC1)C2=NOC(=N2)CN3CCCC(C3)CN4CCOCC4
TargetGlucagon Receptor
SolubilityDMSO:120 mg/mL (292.38 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.75 mM)

Storage & Handling

Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Inhibitor, GCGR, GLP-1, GlucagonReceptor, Glucagon Receptor, inhibit, PAM, obesity-associated diabetes, positive allosteric modulator, V 0219, V0219, V-0219

Similar Products

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  • (S)-V-0219 [orb1744449]

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  • (R)-V-0219 [orb1744450]

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  • (S)-V-0219 hydrochloride [orb1983084]

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  • (R)-V-0219 hydrochloride [orb1983085]

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Key Properties

No computed properties available.

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Protocol Information

V-0219 (orb1301197)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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% DMSO +
%+
% Tween 80 +
%

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1 mg
$ 110.00
DispatchUsually dispatched within 5-10 working days
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