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V-0219 hydrochloride

SKU: orb1689840

Description

V-0219 hydrochloride is an orally bioavailable positive allosteric modulator (PAM) of the GLP-1 receptor. This research compound is used to investigate mechanisms of glucose homeostasis and weight regulation in preclinical models of diabetes and obesity, supporting both in vitro and in vivo studies.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

MW446.89
Purity100.00% (May vary between batches)
FormulaC20H26ClF3N4O2
SMILESFC(F)(C1=CC=C(C2=NOC(CN3CCCC(CN4CCOCC4)C3)=N2)C=C1)F.Cl
TargetGlucagon Receptor
SolubilityDMSO:45 mg/mL (100.7 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.48 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

878453-71-5, 878453-71-5 Free base, Glucagon Receptor, GlucagonReceptor, GLP-1, V 0219 Hydrochloride, V0219 Hydrochloride, V-0219 Hydrochloride, V-0219 hydrochloride(878453-71-5 Free base)

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 100.00
5 mg
$ 180.00
1 ml x 10 mM (in DMSO)
$ 220.00
10 mg
$ 260.00
25 mg
$ 460.00
50 mg
$ 660.00
100 mg
$ 920.00
500 mg
$ 1,880.00
DispatchUsually dispatched within 5-10 working days
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