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Catalog Number | orb2277202 |
---|---|
Category | Small Molecules |
Description | Urumin, a compound with antiviral properties, inhibits human influenza A virus growth, particularly the PR8 strain, with an inhibitory concentration (IC 50) of 3.8 μM. It acts by targeting the conserved stalk of H1 hemagglutinin and can neutralize drug-resistant H1 influenza viruses. Additionally, Urumin offers protective effects against lethal influenza infection in naive mice [1]. |
CAS Number | 2215863-74-2 |
Purity | 98.00% |
MW | 2961.34 |
SMILES | C([C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CN=CN1)C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)C)=O)CS)=O)C)=O)[C@H](CC)C)=O)C)=O)=O)CC(N)=O)=O)CO)=O)=O)CCCNC(=N)N)=O)=O)CS)=O)CCC(N)=O)=O)CO)=O)CC(O)=O)=O)NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CC3=CC=CC=C3)NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC(=O)[C@H]4N(C([C@H]([C@H](CC)C)N)=O)CCC4)CC(C)C)=O)CCCNC(=N)N)=O)=O)C)=O)=O)[C@H](CC)C)=O)CC(N)=O)=O)=O)CCCNC(=N)N)=O)C=5C=6C(NC5)=CC=CC6 |
Formula | C129H198N42O35S2 |
Biological Activity | Urumin, a compound with antiviral properties, inhibits human influenza A virus growth, particularly the PR8 strain, with an inhibitory concentration (IC 50) of 3.8 μM. It acts by targeting the conserved stalk of H1 hemagglutinin and can neutralize drug-resistant H1 influenza viruses. Additionally, Urumin offers protective effects against lethal influenza infection in naive mice [1]. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 95% by hplc | |
2959.44 Da | |
H-Ile-Pro-Leu-Arg-Gly-Ala-Phe-Ile-Asn-Gly-Arg-Trp-Asp-Ser-Gln-Cys-His-Arg-Phe-Ser-Asn-Gly-Ala-Ile-Ala-Cys-Ala-OH |