Urumin

• Catalog Number: orb1479251
• Category: Proteins
• Description: Antiviral host defense peptide; Antimicrobial peptides.
• Form/Appearance: Freeze dried solid
• Purity: > 95% by hplc
• MW: 2959.44 Da
• Formula: C₁₂₉H₁₉₈N₄₂O₃₅S₂
• Structure: H-Ile-Pro-Leu-Arg-Gly-Ala-Phe-Ile-Asn-Gly-Arg-Trp-Asp-Ser-Gln-Cys-His-Arg-Phe-Ser-Asn-Gly-Ala-Ile-Ala-Cys-Ala-OH
• Solubility (25°C): Soluble in water
• Protein Sequence: IPLRGAFINGRWDSQCHRFSNGAIACA
• Storage: Store dry, frozen and in the dark
• Alternative names: AM350, IPLRGAFINGRWDSQCHRFSNGAIACA, Urumin
• Background: Urumin is a 27-amino acid virucidal host defense peptide, originally isolated from the skin of the South Indian frog Hydrophylax bahuvistara. Urumin is virucidal for H1 hemagglutinin bearing human influenza A viruses, in which it specifically targets the conserved stalk region of H1 hemagglutinin, and is effective against drug-resistant H1 influenza viruses that are resistant to oseltamivir, zanamivir and peramivir. Urumin appears to inhibit viral growth by physically destroying influenza virions, and can also protect naive mice from lethal influenza infection in vivo.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Structure for Urumin