UNC0631

SKU: orb1223345

Description

UNC-0631 is a novel G9a inhibitor with excellent potency in a variety of cell lines and excellent separation of functional potency versus cell toxicity. Protein lysine methyltransferase G9a plays key roles in the transcriptional repression of a variety of genes via dimethylation of lysine 9 on histone H3 (H3K9me2) of chromatin as well as dimethylation of nonhistone proteins including tumor suppressor p53.

Key Properties

• CAS Number: 1320288-19-4
• MW: 635.93
• Purity: >98% (HPLC)
• Formula: C₃₇H₆₁N₇O₂
• SMILES: COc1c(OCCCN2CCCCC2)cc2nc(nc(NC3CCN(CC4CCCCC4)CC3)c2c1)N1CCCN(CC1)C(C)C
• Target: EGFR
• Solubility: DMSO : 16.67 mg/mL. 26.21 mM; H2O : < 0.1 mg/mL

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

UNC0631, UNC 0631, UNC-0631

Quick Database Links

Gene Symbol

EGFR