UDP disodium salt

SKU: orb1221492

Description

UDP is a specific agonist of the P2Y6 receptors (EC50 = 13 nM for human P2Y6) stimulating the production of inflammatory mediators phagocytosis and vasoconstriction. UDP also acts as an antagonist of P2Y14.

Key Properties

• CAS Number: 27821-45-0
• MW: 466.14
• Purity: >98% (HPLC)
• Formula: C₉H₁₄N₂Na₂O₁₃P₂
• SMILES: [Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP(O)([O-])=O)n1ccc(=O)[nH]c1=O
• Target: P2 Receptor
• Solubility: DMSO:10 mM

Bioactivity

• In Vitro:
  RT-PCR Cell line: Primary microglia. Concentration: 100 μM. Incubation time: For 15 min. Result: Significantly induced microglial CCL2 and CCL3 mRNA expression.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Uridine 5'-diphosphate disodium salt hyd

Quick Database Links

Gene Symbol

P2 Receptor