Uridine 5′-diphosphoglucose disodium salt

SKU: orb1302600

Description

Uridine 5′-diphosphoglucose disodium salt is an endogenous nucleotide sugar serving as a glycosyl donor in metabolic glycosylation reactions. It acts as a potent P2Y14 receptor agonist (EC50 = 0.35 μM) and can also activate GPR17 to promote oligodendrocyte differentiation in vitro, making it a key tool for studying purinergic signaling and cell differentiation.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 28053-08-9
• MW: 610.27
• Purity: >99.99% (May vary between batches)
• Formula: C₁₅H₂₂N₂Na₂O₁₇P₂
• SMILES: [Na+].[Na+].OC[C@@H](OP(=O)(OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O)OP([O-])([O-])=O)[C@@H](O)[C@H](O)[C@@H](O)C=O
• Target: P2Y Receptor,Endogenous Metabolite
• Solubility: H2O:125 mg/mL (204.83 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (8.19 mM);DMSO:128.75 mg/mL (210.97 mM)

Bioactivity

• Target IC50:
  P2Y14 receptor:0.35 μM (EC50)

Storage & Handling

• Storage: store under nitrogen,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, P2YReceptor, P2Y Receptor, P2Y14, P2Y, Inhibitor, Endogenous Metabolite, EndogenousMetabolite, UDP-Glucose sodium, UDP-Glucose sodium salt, UDP-a-D-Glucose sodium, UDP-alpha-D-Glucose sodium, UDPG sodium, UDPG sodium salt, UDP-α-D-Glucose sodium, UDP-α-D-Glucose sodium salt, Uridine 5′ diphosphoglucose disodium salt, Uridine 5′-diphosphoglucose, Uridine 5′-diphosphoglucose disodium, Uridine 5′diphosphoglucose disodium salt, Uridine 5'-diphosphoglucose disodium sal

Compound Identifiers

PubChem CID

90470765