Tyrosine kinase-IN-7

SKU: orb2900438

Description

Tyrosine kinase-IN-7 (compound 13h) is an inhibitor of the tyrosine kinase EGFR. The IC50s for inhibiting EGFR(WT) and EGFR(T790M) are 0.630 μM and 0.956 μM respectively. Tyrosine kinase-IN-7 has antitumor activity against four cancer cell lines (HepG2, HCT-116, MCF-7, and A431) with IC50s of 13.02 μM, 10.14 μM, 12.68 μM, and 47.05 μM, respectively.

Key Properties

• CAS Number: 345615-74-9
• MW: 297.38
• Purity: >98% (HPLC)
• Formula: C₁₆H₁₅N₃OS
• SMILES: OC1=CC=C(NC2=NC=NC3=C2C2=C(CCCC2)S3)C=C1
• Target: Antiviral

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Antiviral