Tyrosine kinase-IN-7

SKU: orb1944729

Description

Tyrosine kinase-IN-7 is a potent EGFR inhibitor active against both wild-type and T790M mutant forms. It demonstrates anti-cancer activity in various cell lines and has shown potential in anti-inflammatory and antiviral research contexts in preclinical studies.

Research Area

Cardiovascular Research, Immunology & Inflammation, Signal Transduction

Key Properties

• CAS Number: 345615-74-9
• MW: 297.38
• Purity: 99.93% (May vary between batches)
• Formula: C₁₆H₁₅N₃OS
• SMILES: OC1=CC=C(NC2=NC=NC3=C2C2=C(CCCC2)S3)C=C1
• Target: EGFR,Antiviral
• Solubility: DMSO:5.5 mg/mL (18.49 mM)

Bioactivity

• Target IC50:
  EGFR (T790M):0.956 μM|EGFR (WT):0.63 μM

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

EGFR, Antiviral, TyrosinekinaseIN7

Compound Identifiers

PubChem CID

769491