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TWS119

SKU: orb1224515

Description

A GSK-3β inhibitor with IC50 of 30 nM in a cell-free assay; can induce neurogenesis in murine ESCs; reduces Cdon levels and aberrant Cx43 activitiesin rat cardiomyocytes; attenuates rtPA-induced hemorrhagic transformation and activates the Wnt/β-catenin signaling pathway after acute ischemic stroke in rats.

Images & Validation

Key Properties

CAS Number601514-19-6
MW318.3293
Purity>98% (HPLC)
FormulaC18H14N4O2
SMILESC1=CC(=CC(=C1)N)C2=CC3=C(N2)N=CN=C3OC4=CC=CC(=C4)O
TargetGSK-3
Solubility10 mM in DMSO

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

TWS 119 | TWS-119

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TWS119 (orb1224515)

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Available Sizes

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200 mg
500 mg
5 mg
$ 80.00
10 mg
$ 110.00
25 mg
$ 190.00
50 mg
$ 330.00
100 mg
$ 540.00