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Catalog Number | orb1302823 |
---|---|
Category | Small Molecules |
Description | Tucidinostat |
CAS Number | 1616493-44-7 |
Purity | 98.76% |
MW | 390.41 |
SMILES | Nc1cc(F)ccc1NC(=O)c1ccc(CNC(=O)\C=C\c2cccnc2)cc1 |
Formula | C22H19FN4O2 |
Biological Activity | Tucidinostat (Chidamide) is an effective and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, less active on HDAC8/11 (IC50: 733/432 nM), and shows no effect on HDAC4/5/6/7/9. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |