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Tubulin inhibitor 6

SKU: orb1308986

Description

Tubulin inhibitor 6 (iHAP1) is a small molecule that disrupts microtubule polymerization, demonstrating potent anti-proliferative activity against various cancer cell lines in vitro. Its mechanism supports research in oncology, particularly in studying mitotic arrest and apoptosis in cellular models.

Research Area

Pharmacology & Drug Discovery; Cell Biology, Signal Transduction

Images & Validation

Key Properties

CAS Number105925-39-1
MW367.85
Purity99.53% (May vary between batches)
FormulaC20H14ClNO2S
SMILESCOc1ccc(cc1)C(=O)N1c2ccccc2Sc2ccc(Cl)cc12
TargetMicrotubule Associated
SolubilityDMSO:40 mg/mL (108.74 mM);10% DMSO+90% Corn Oil:4 mg/mL (10.87 mM)

Bioactivity

Target IC50
Tubulin polymerization:0.87 μM (IC50)
In Vitro
Tubulin inhibitor 6 exhibits submicromolar antiproliferative activity.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

DLD-1, cycle, cell, COLO-205, Antiproliferative, BT549, 451LU, Microtubule/Tubulin, MicrotubuleAssociated, Microtubule Associated, NCIH460, K562, inhibit, Inhibitor, iHAP1, SKOV3, SW480, tubulin, tubulin polymerization, Tubulin inhibitor 6, Tubulin inhibitor6, Tubulin inhibitor-6

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Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

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1 ml x 10 mM (in DMSO)
$ 70.00
10 mg
$ 80.00
25 mg
$ 90.00
50 mg
$ 120.00
100 mg
$ 160.00
DispatchUsually dispatched within 5-10 working days
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