TTP 22

SKU: orb1307365

Description

TTP 22 is a potent and selective ATP-competitive inhibitor of casein kinase 2 (CK2), exhibiting an IC50 of 0.1 µM and a Ki of 40 nM. It demonstrates over 250-fold selectivity against kinases such as JNK3, ROCK1, and MET. This inhibitor is a valuable chemical probe for studying CK2 signaling in cancer and cellular biology research, applicable in both in vitro and cell-based assays.

Research Area

Metabolism Research, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 329907-28-0
• MW: 330.42
• Purity: 97.78%
• Formula: C₁₆H₁₄N₂O₂S₂
• SMILES: Cc1ccc(cc1)-c1csc2ncnc(SCCC(O)=O)c12
• Target: Casein Kinase
• Solubility: DMSO:50 mg/mL (151.32 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.05 mM)

Bioactivity

• Target IC50:
  CK2:0.1 μM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Casein Kinase, CaseinKinase, CK2, inhibit, Inhibitor, TTP22, TTP-22, TTP 22

Compound Identifiers

PubChem CID

1536915