TTP 22

SKU: orb1225290

Description

TTP 22 is a high affinity, ATP-competitive casein kinase 2 (CK2) inhibitor with IC50/Ki of 0.1 uM/40 nM; shows selectivity for CK2 over JNK3, ROCK1, and MET(IC50> 10 uM).

Key Properties

• CAS Number: 329907-28-0
• MW: 330.42
• Purity: >98% (HPLC)
• Formula: C₁₆H₁₄N₂O₂S₂
• SMILES: O=C(O)CCSC1=C(C(C2=CC=C(C)C=C2)=CS3)C3=NC=N1
• Target: Casein Kinase
• Solubility: DMSO: 100 mg/mL

Bioactivity

• In Vitro:
  TTP 22 is a potent CK2 inhibitor, with an IC50 of 100 nM and a Ki of 40 nM. TTP 22 shows no effect on other kianses such as Jnk3, Rock1, Tie2, Ask1, Met and FGFR1 at 10 μM.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

TTP 22 | TTP-22 | TTP22

Quick Database Links

Gene Symbol

Casein Kinase