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TTP 22

SKU: orb1225290

Description

TTP 22 is a high affinity, ATP-competitive casein kinase 2 (CK2) inhibitor with IC50/Ki of 0.1 uM/40 nM; shows selectivity for CK2 over JNK3, ROCK1, and MET(IC50> 10 uM).

Images & Validation

Key Properties

CAS Number329907-28-0
MW330.42
Purity>98% (HPLC)
FormulaC16H14N2O2S2
SMILESO=C(O)CCSC1=C(C(C2=CC=C(C)C=C2)=CS3)C3=NC=N1
TargetCasein Kinase
SolubilityDMSO: 100 mg/mL

Bioactivity

In Vitro
TTP 22 is a potent CK2 inhibitor, with an IC50 of 100 nM and a Ki of 40 nM. TTP 22 shows no effect on other kianses such as Jnk3, Rock1, Tie2, Ask1, Met and FGFR1 at 10 μM.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

TTP 22 | TTP-22 | TTP22

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  • TTP 22 [orb1307365]

    97.78% (May vary between batches)

    329907-28-0

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    C16H14N2O2S2

    5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 1 mg, 1 ml x 10 mM (in DMSO)
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Protocol Information

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200 mg
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5 mg
$ 130.00
10 mg
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$ 380.00
50 mg
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100 mg
$ 800.00