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TRPV4 agonist-1

SKU: orb1708318

Description

TRPV4 agonist-1 is a potent and selective small molecule activator of the TRPV4 ion channel, demonstrating an EC50 of 60 nM in human TRPV4 calcium influx assays. This compound is a valuable research tool for investigating TRPV4-mediated signaling in physiological and pathological contexts, including studies of osmoregulation, pain, and vascular function in both cellular and animal models.

Research Area

Pharmacology & Drug Discovery, Pharmacology & Drug Discovery; Cell Biology

Images & Validation

Key Properties

CAS Number2314467-60-0
MW484.93
FormulaC25H23ClF2N4O2
SMILESO=C1N(C2=CC=C(OC3=CC=C(F)C=C3)C=C2)C(N4CCN(C)CC4)=NC5=C1C=CC=C5F.[H]Cl
TargetTRP/TRPV Channel

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Protocol Information

TRPV4 agonist-1 (orb1708318)

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Available Sizes

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25 mg
$ 1,560.00
50 mg
$ 2,020.00
100 mg
$ 2,540.00
DispatchUsually dispatched within 6-8 weeks
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