TRPV3 Antibody (APC)

SKU: orb148704

Description

Mouse monoclonal to TrpV3 (APC). The TRPV3 protein belongs to a family of non-selective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. The thermo sensitive members of this family are expressed in subsets of sensory neurons that terminate in the skin, and are activated at distinct physiological temperatures. This channel is activated at temperatures between 22 and 40 degrees C. The gene lies in close proximity to another family member (TRPV1) gene on chromosome 17, and the two encoded proteins are thought to associate with each other to form heteromeric channels.

Research Area

Neuroscience

Images & Validation

• Tested Applications: AM, ICC, IF, IHC, IP, WB
• Dilution Range: WB (1:1000), IHC (1:1000), ICC/IF (1:100)
• Reactivity: Human, Mouse, Rat
• Application Notes:
  1 µg/ml was sufficient for detection of TrpV3 in 10 µg of COS-1 cell lysate transiently transfected with TrpV3 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody

Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG2a
• Clone No.: N15/39 (Formerly sold as S15-39)
• Immunogen: Synthetic peptide amino acids 458-474 (cytoplasmic C-terminus) of rat TrpV3
• Target: TRPV3
• Molecular Weight: 70kDa
• Purification: Protein G Purified
• Conjugation: APC

Storage & Handling

• Storage: Conjugated antibodies should be stored according to the product label
• Buffer/Preservatives: 95.46mM Phosphate, 2.48mM MES and 2mM EDTA
• Concentration: 1 mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

1110036I10Rik, MGC124324, MGC124325, Transient receptor potential cation channel subfamily V member 3, TrpV3, Trpv3 heat sensitive channel, TRPV3_HUMAN, Vanilloid receptor 3, Vanilloid receptor like 3, Vanilloid receptor-like 3, vanilloid receptor-related osmotically activated channel protein, VRL 3, VRL-3, VRL3, vanilloid receptor 2, sensitive channel TRPV3

Quick Database Links

Gene Symbol

TRPV3

UniProt

Q4QYD9

NCBI Gene ID

497948

RefSeq (Protein):NP_001020928