TRP1 / Tyrosinase-Related Protein-1 Antibody

• Catalog Number: orb385760
• Category: Antibodies
• Description: It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: TA99
• Tested applications: FACS, IF, IHC-Fr
• Reactivity: Human, Mouse
• Isotype: Mouse IgG2a, kappa
• Immunogen: SK-MEL-23 cells were used as the immunogen for this TRP1 antibody.
• Dilution range: Flow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml,Immunohistochemistry (Frozen): 1-2ug/ml for 30 min at RT
• Purity: Protein G affinity chromatography
• Conjugation: Unconjugated
• Formula: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
• Hazard Information: This TRP1 antibody is available for research use only.
• UniProt ID: P17643
• Storage: Store the TRP1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
• Buffer/Preservatives: 0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin (US sourced) and 0.05% sodium azide
• Note: For research use only
• Application notes: The optimal dilution of the TRP1 antibody for each application should be determined by the researcher.
• Expiration Date: 12 months from date of receipt.