TRIB3 Rabbit mAb [KD Validated] Antibody

SKU: orb1950715

Description

Disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. May bind directly to and mask the 'Thr-308' phosphorylation site in AKT1. Binds to ATF4 and inhibits its transcriptional activation activity. Interacts with the NF-kappa-B transactivator p65 RELA and inhibits its phosphorylation and thus its transcriptional activation activity.

Images & Validation

• Tested Applications: IP, WB
• Dilution Range: WB 1:1000~1:5000 IP 1:20
• Reactivity: Human

Key Properties

• Antibody Type: Recombinant Antibody
• Host: Rabbit
• Clonality: Monoclonal
• Isotype: Rabbit IgG
• Immunogen: A synthesized peptide derived from human TRIB3
• Purification: Affinity-chromatography
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

NIPK; SINK; SKIP3; TRB3; Trib3; Tribbles3;

All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.

Western blot analysis of TRIB3 expression in 293T cell lysate.

Quick Database Links

UniProt

Q96RU7