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| Catalog Number | orb1950715 |
|---|---|
| Category | Antibodies |
| Description | Disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. May bind directly to and mask the 'Thr-308' phosphorylation site in AKT1. Binds to ATF4 and inhibits its transcriptional activation activity. Interacts with the NF-kappa-B transactivator p65 RELA and inhibits its phosphorylation and thus its transcriptional activation activity. |
| Clonality | Recombinant |
| Species/Host | Rabbit |
| Isotype | Rabbit IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Form/Appearance | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification | Affinity-chromatography |
| Immunogen | A synthesized peptide derived from human TRIB3 |
| UniProt ID | Q96RU7 |
| Tested applications | IP, WB |
| Dilution range | WB 1:1000~1:5000 IP 1:20 |
| Antibody Type | Recombinant Antibody |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Alternative names | NIPK; SINK; SKIP3; TRB3; Trib3; Tribbles3; |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
![TRIB3 Rabbit mAb [KD Validated]](/images/pub/media/catalog/product/NewWebsite/18/orb1950715_1.png)
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
![TRIB3 Rabbit mAb [KD Validated]](/images/pub/media/catalog/product/NewWebsite/18/orb1950715_2.png)
Western blot analysis of TRIB3 expression in 293T cell lysate.
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